Research

Asymmetric catalysis

Professor Carlos Correia’s main research interest include the development of new synthetic methodologies involving palladium, enantioselective catalysis, and organic synthesis aiming at the synthesis of natural products, bioactive heterocyclic compounds, pharmaceuticals and functional compounds in a concise and practical manner

 

The Heck-Matsuda reaction is one of our major interests.

 

Arenediazonium tetrafluoroborates are extremely easy-handle substrates. They have scalable synthesis, can be isolated and stored up to several months without risk. Their reactivity towards palladium catalysis improves the opportunities for efficient and mild arylation methods.

 

 

Medicinal Chemistry

Since 2012, the Correia’s group has been using its expertise in heterocycles chemistry for medicinal purposes. The group has already synthesized a large number of marinoquinolines, a privileged scaffold that is showing promising results as new antimalarial and antibacterial agents.

Such projects involve the important collaboration of the research groups of Prof. Rafael Guido (USP/São Carlos, Brazil), and Concepción González-Bello (CiQUS/Santiago de Compostela/Spain).